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07 Mar '19

Preventing and Treating Skin Infections in the Elderly with Ozonated Oil

Posted by Marin Crangaci
Skin and soft tissue infections are quite common in elderly people. A number of special conditions and circumstances need to be considered in the diagnosis and therapy. It is important to try to establish the causative organism, exclude other cutaneous disorders and identify precipitating factors. Treatment modalities include antiseptics, topical and systemic antibacterials, dressings and biotherapy. Skin infections presenting with erythema, blisters, pustules, and ulcerations. Cellulitis and infected ulcers are the most commonly encountered cutaneous infections in the elderly. Accurate and quick diagnosis and treatment are imperative to prevent significant morbidity and mortality.

Prevent Skin Infections in the Elderly with Ozonated oil

The best way to prevent skin infections is to keep skin healthy and intact. 

Ozonated oil does a great job with it because:

  • It protects the skin against external aggressors.
  • It is deeply moisturizing and nourishing.
  • It purifies, regenerates and repairs the skin. It helps the healing process.
  • It improves blood circulation and associated problems (ulcers, severe dry skin…).
  • It controls and prevents the proliferation of germs present in some skin conditions (acne, seborrhea, skin lesions…).
  • It improves cellular metabolism and strengthens the natural anti-inflammatory system.
  • It treats problematic or damaged skin (redness, bedsores, scars...).
  • It helps to avoid the use of medical treatments such as corticosteroid creams.

Ozonated olive oil for treating bacterial skin infections

The excessive consumption of antibiotics for the treatment of infectious diseases has fuelled the drug resistance phenomenon, i.e., the microorganisms are resistant to antibiotics. Therefore, it is necessary to develop new molecules with antibiotic properties, preferably natural and nonsynthetic. In fact, this research is divided into the field of synthetic molecules produced by the chemical/ pharmaceutical industry and the field of natural active compounds, in which plant extracts are studied also by the use of green chemistry. The plants are able to withstand fungal and bacterial infections and therefore their secondary metabolites can be applied in the field of medicinal herbs. Maoz and Neeman in their research reported an antifungal action of olive oil due to the high content of oleic acid. The ozonated oil increases this natural capacity, because ozone acts on microorganisms, thanks to its greater oxidizing power; in fact, it is able to break down the macromolecules that are the basis of the vital integrity of bacterial cells, fungus, protozoa, and viruses. The ozone in contact with the microorganism’s lipoproteins forms H2O2 and the final products of lipid oxidation (LOP); H2O2 assures bacteriostatic and bactericidal activity, while final lipid oxidation products have induction activity and reactivate metabolic functions. Nagayoshi et al. reported the capability of ozone to destroy Gram-positive and -negative microorganisms, and in particular, Gram-negative bacteria are more sensitive.

The ozonated oil easily penetrate the cell membrane and, thanks to their biological properties, stimulate skin cells and improve the tropism of the skin by promoting wound healing and repair of ulcers of various kinds; from the experiments, it was found that topical application of products based on ozonides has determined a considerable increase of fibroblasts resulting in increased production of collagen, glycosoaminoglycans, and formation of elastic and reticular fibers. The healing of skin lesions includes complex movements like tissue hemorrhage, inflammation, re-epithelialization, granulation tissue, and finally remodeling. These events involve the coordination of many cell types and matrix proteins, which are important for the control of the various stages of tissue repair. Previous studies have shown that endogenous growth factors, such as fibroblast growth factor (FGF), growth factor derived from platelets (PDGF), the TGF-β factor, and vascular endothelial growth factor (VEGF) are important regulators in the healing of wounds. They are released by macrophages, fibroblasts, and keratinocytes at the site of injury and participate in the regulation of re-epithelialization, formation of granulation tissue, collagen synthesis, and neovascularization. The beneficial effects of ozone in the treatment of sores are due to the decrease of bacterial infection and the increasing oxygen tension in the wound. In the literature, it is reported that after exposure to ozone transcription factors are activated, such as NF-kB, and these are important regulators of the inflammatory response and tissue repair process.

In conclusion, the ozonated olive oil can accelerate acute cutaneous wound repair, by stimulation of dermal fibroblast, and the ozonized oil has shown to be effective against Gram-negative and -positive bacteria, mycetes, and viruses, so it can be used for the cure of infections.

 


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