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The prevalence of Diabetes Mellitus (DM) is estimated to be about 300 million people worldwide. Poor diabetes control may lead to complications such as diabetic foot ulcers or amputations. The high incidence of amputation is still considered as an important socio-economic problem. The increased incidence of diabetes increases the incidence of diabetic foot ulcers. Patients with diabetic foot ulcers may also be at high risks of mortality due to the associated cardiovascular diseases. Foot ulcers are one of the most important chronic complications of diabetes and are regarded as a major problem which significantly affects the quality of life. Diabetic...

Peptic ulcer, one of the most common gastrointestinal diseases, is a chronic inflammatory disease characterized by ulceration in the regions of the upper gastrointestinal tract where parietal cells are found and where they secrete hydrochloric acid and pepsin. The anatomical sites where ulcer occurs commonly are stomach and duodenum, causing gastric and duodenal ulcer, respectively. Physiopathology of ulcer is due to an imbalance between aggressive factors, such as acid, pepsin, Helicobacter pylori and non-steroidal anti-inflammatory agents, and local mucosal defensive factors, such as mucus bicarbonate, blood flow and prostaglandins. Several drugs are widely used to prevent or treat gastro-duodenal ulcers. These...

Nothing quite takes the fun out of a backyard barbeque as much as an insect invasion. For the most part, these creepy-crawly or flying critters pose a minor annoyance, but sometimes their bites or stings can cause severe allergic reactions, infections, or diseases such as West Nile virus or Lyme disease. The best way to avoid bites and stings is, of course, to minimize contact with insects. Simple steps, such as wearing light-colored, long-sleeved clothing and using insect repellents when insect exposure is likely, help to reduce the likelihood of insect bites or stings. Homeowners can also take precautions such...

Topical application of ozonated oil allow using of high concentrations of ozone, which have a direct oxidative effect on the membrane of the microorganisms. Ozone kills almost all types of bacteria, fungi, viruses and protozoa. It provide a bactericidal action, as well as transfer active oxygen to tissues, accelerate wound healing processes, and have a significant antifungal effect. Ozonated oils are successfully used for the treatment of burns and skin diseases. Ozonated oil is stored in a dark glass container.  Its quality is largely dependent on storage temperature. It retains activity at room temperature - 3 months, when in the...